Industry Applications
Subzero Engineering’s Simplex modular clean rooms were developed with custom applications in mind. The possibilities are endless. Whatever the unique requirement, our team brings industry expertise and a proactive approach to solving even the most difficult isolation challenges.
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Portable Cleanroom Solutions Across Critical Environments
Portable Cleanroom Solutions Across Critical Environments
From biotech research to aerospace manufacturing, our modular clean room systems provide contamination control for diverse applications requiring flexibility, compliance, and rapid deployment.
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Biotech R&D Labs
Biotech R&D Labs
Prefab clean rooms for cell culture work, genetic research, and prototype development. Modular systems adapt as research priorities shift, providing ISO Class 5-8 environments without permanent facility modifications.
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E-Liquid & Vape Production
E-Liquid & Vape Production
FDA-compliant mobile clean room environments for e-cigarette and vaping products. Our instant cleanroom solutions meet current regulatory requirements while allowing production scaling and facility changes.
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Aerospace Component Assembly
Aerospace Component Assembly
Portable cleanrooms for satellite components, avionics assembly, and precision manufacturing. Mobile systems accommodate project-based work and varying contamination control requirements.
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Temporary Hazmat Isolation Rooms
Temporary Hazmat Isolation Rooms
Emergency containment using modular clean room technology for hazardous material handling, decontamination procedures, and environmental remediation. Systems deploy quickly for critical response situations.
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Medical Device Packaging
Medical Device Packaging
Prefabricated clean room environments for sterile packaging that can be established in existing facilities without major renovations. Meet FDA and ISO requirements while maintaining operational flexibility.
Mobile Clean Room vs. Permanent Cleanrooms: Performance Comparison
| Feature | Mobile Cleanrooms | Permanent Cleanrooms |
| Install Time | 3-5 Days | 6-12 Weeks |
| Reconfigurability | Complete Flexibility | Limited Modifications |
| Compliance | Full ISO Classifications | Full ISO Classifications |
| Initial Cost | 40–60% Lower | Higher Upfront Investment |
| Relocation | Complete Portability | Fixed Installation |
| Expansion | Modular Additions | Requires Construction |
Why Choose Portable Cleanrooms?
When your contamination control needs to include project-based work, uncertain facility futures, or budget constraints, modular clean room systems deliver identical performance with operational advantages permanent installations cannot match. All Subzero portable systems are compatible with ISO classifications, and can be designed to support USP 797/800 requirements.
Selection Criteria for Your Application
Choosing the right portable cleanroom configuration depends on your specific operational requirements, compliance needs, and facility constraints. Consider these key factors when evaluating modular clean room options for your project.

Airflow & Filtration Configuration
- Unidirectional vs. turbulent airflow patterns
- HEPA and ULPA filtration capabilities
- Custom air change rates based on classification requirements

Wall System Options
- Hardwall: Maximum durability for permanent temporary installations
- Softwall: Ultimate flexibility for changing requirements
- Hybrid: Combining rigid framework with flexible panels

Entry and Access Systems
- Personnel entry configurations (single, dual, airlock)
- Material transfer systems and pass-throughs
- Emergency egress and safety compliance

Mobility Requirements
- Fully portable cleanrooms for complete relocation
- Semi-permanent installations with reconfiguration capability
- Modular clean room expansion options for growing operations

Size and Layout
- Standard configurations from 8×8 feet to custom dimensions
- Multi-room complexes and interconnected environments
- Ceiling height options from 8-12 feet

Compliance Specifications
- ISO 14644 classifications (Class 5-8 most common)
- USP 797 and USP 800 pharmaceutical standards
- Industry-specific regulatory requirements
Product Categories
Our comprehensive product portfolio serves critical environments across pharmaceutical, electronics, aerospace, and biotechnology industries. With thousands of successful installations worldwide, these modular clean room components have proven their reliability in the most demanding applications.
Trusted by Fortune 500 companies across pharmaceutical, electronics, and aerospace industries for critical contamination control.
Modular Clean Room Manufacturers: Why Subzero Engineering
35+ Years Combined Experience
As one of the leading prefabricated clean room manufacturers, we have engineered contamination control solutions since before modular systems became industry standard.
Proven Results
Our portable cleanroom installations achieve identical contamination control performance to permanent facilities while reducing deployment time by 75%.
Global Support
In-house manufacturing across state-of-the-art facilities with local expertise through regional partners and support teams.
Consultative Approach
We start by asking “What do you want to achieve?” rather than trying to fit existing solutions to your specific requirements.
Simplification
In 2022, a spacecraft infrastructure company received a contract to manufacture parts for the International Space Station Earth Observatory. Simplex provided fifteen separate ISO 5 cleanrooms at their manufacturing facility. Each 12′ x 12′ x 11′ cleanroom was constructed with softwall panels mounted on casters for easy portability. The modular design allowed panel frames to be disassembled and reconfigured into a larger 36′ x 60′ x 11′ room when project requirements changed.
This flexibility proved essential when production demands shifted, demonstrating exactly why portable cleanroom systems deliver operational advantages permanent installations cannot match.
Frequently Asked Questions
What is a portable cleanroom?
A portable cleanroom is a modular contamination control environment that can be quickly assembled, disassembled, and relocated. These mobile clean room systems maintain the same ISO classifications and regulatory compliance as permanent installations.
How much does a portable cleanroom cost?
Portable cleanrooms typically start around $100-150 per square foot for basic softwall configurations. A standard 10′ x 10′ portable cleanroom would range from $10,000-$15,000, representing 40-60% savings compared to permanent construction. Final pricing depends on ISO classification requirements, specialized features, and installation complexity.
What’s the difference between a clean room and sterile room?
Clean room tents and modular systems control airborne particulates to specific contamination levels (ISO classifications). Sterile rooms eliminate all viable microorganisms. Many applications require cleanroom environments rather than full sterility.
Do portable cleanrooms meet OSHA compliance requirements?
Yes. Our prefab clean rooms are engineered to meet all applicable safety and regulatory standards including OSHA requirements, fire codes, and industry-specific regulations.
What types of instant cleanroom solutions are available?
We offer hardwall, softwall, and hybrid configurations. Hardwall provides maximum durability, clean room tents offer ultimate flexibility, and hybrid systems combine rigid frameworks with flexible panels.
How easily can mobile cleanrooms be relocated?
Complete relocation typically requires 1-2 days for disassembly and 3-5 days for reassembly at the new location. All components are labeled and documented for efficient reinstallation.
Modular Clean Room Applications
Subzero Engineering’s Simplex modular clean rooms were developed with custom applications in mind. The possibilities are endless. Whatever the unique requirement, our team brings industry expertise and a proactive approach to solving even the most difficult isolation challenges.
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Aerospace + Defense
Aerospace + Defense
We understand the complex nature of the aerospace and defense manufacturing industry.
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ELECTRONICS MANUFACTURING
ELECTRONICS MANUFACTURING
Modular enclosure solutions for high sensitivity electronics manufacturing environments.
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E-LIQUID MANUFACTURING
E-LIQUID MANUFACTURING
We engineer custom e-liquid, e-cigarette, e-juice manufacturing cleanrooms compliant with current FDA regulations.
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FOOD PREPARATION
FOOD PREPARATION
Ensure a contamination free environment to process, prep, and package food.
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HAZMAT HANDLING
HAZMAT HANDLING
Simplex cleanrooms can be custom designed to deal with the complex handling and storage of hazardous materials.
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LASER MANUFACTURING
LASER MANUFACTURING
Airborne contaminants can wreak havoc on lasers; Safeguard your critical laser environment.
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Manufacturing Applications
Manufacturing Applications
Simplex cleanrooms and separation products create a variety of solutions for manufacturing facilities.
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MEDICAL APPLICATIONS
MEDICAL APPLICATIONS
Simplex cleanrooms can be designed to efficiently Meet and Exceed Industry Regulatory Requirements.
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PHARMECEUTICAL COMPOUNDING
PHARMECEUTICAL COMPOUNDING
We have designed numerous cleanrooms for use in the pharmaceutical industry.
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TEMPORARY & PORTABLE
TEMPORARY & PORTABLE
Temporary/portable cleanrooms can be designed using hardwall or softwall configurations and can quickly be expanded or relocated.
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